You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air

https://westcentrallocalbusiness.blob.core.windows.net/my-home-blog/why-escondido-homeowners-are-investing-in-attic-rodent-proofing.html

You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air and raise the risk of exposure to rodent-borne diseases.